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Transthyretin amyloidosis (ATTR) is a rare condition where a protein called transthyretin becomes unstable and forms clumps, known as amyloid, that build up in the body’s organs, especially the heart and nerves. This can lead to serious health problems over time. There are two main types: hereditary ATTR (hATTR), which is passed down through families, and wild-type ATTR (wtATTR), which usually develops with age. While ATTR is serious, there are now several effective treatment options that can help slow its progression and improve quality of life. Here's a closer...

Immune thrombocytopenia (ITP) is a condition where the body’s immune system attacks its own platelets, which help the blood to clot. With fewer platelets, people with ITP may bruise or bleed more easily than normal. Although the condition can seem scary, many treatment options can help manage the symptoms and improve quality of life. In this article, we explain 12 common treatment methods for ITP, including medical, lifestyle and natural remedies. Hizentra is a type of immunoglobulin, a medicine made from the antibodies found in healthy donors. It is...

Brain tumors can affect people of all ages and backgrounds. While the idea of a brain tumor can be scary, understanding the signs and symptoms can help with early detection and treatment. In this article, we’ll look at ten of the most common symptoms, why they happen and when you should see a doctor. Frequent or worsening headaches are a well-known symptom of brain tumors. They may: Not every headache means you have a brain tumor, but a new pattern of headaches is worth investigating. Brain tumors can trigger...

Transthyretin amyloid cardiomyopathy (ATTR-CM) is an underdiagnosed condition in which misfolded transthyretin (TTR) proteins build up in the heart tissue, leading to stiffening of the heart muscle. Over time, this can cause restrictive cardiomyopathy and heart failure—and, in some cases, heart attack. Unlike typical heart attacks caused by blocked arteries, cardiac events related to ATTR-CM often result from the heart’s inability to pump efficiently due to the thickened, stiffened walls. This difference means the warning signs of a heart attack caused by ATTR-CM may be subtler or mistaken for...