Warning Signs of a Heart Attack Due to ATTR-CM
Transthyretin amyloid cardiomyopathy (ATTR-CM) is an underdiagnosed condition in which misfolded transthyretin (TTR) proteins build up in the heart tissue, leading to stiffening of the heart muscle. Over time, this can cause restrictive cardiomyopathy and heart failure—and, in some cases, heart attack. Unlike typical heart attacks caused by blocked arteries, cardiac events related to ATTR-CM often result from the heart’s inability to pump efficiently due to the thickened, stiffened walls. This difference means the warning signs of a heart attack caused by ATTR-CM may be subtler or mistaken for...